epratuzumab

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epratuzumab

GtoPdb Ligand ID: 8088

Compound class: Antibody

Comment: Epratuzumab is a humanized monoclonal antibody. It is derived from the murine IG2a monoclonal antibody, LL2 (EPB-2). Epratuzumab has antineoplastic and antiinflammatory actions [1].
The antibody can be conjugated with tetraxetan (DOTA) which allows chelation of radionucleotides such as yttrium-90 [5].

Summary
Biological activity
Clinical data
References
Immunopharmacology

Bioactivity Comments
We have been unable to find a publicly available binding affinity for interaction between epratuzumab and CD22. However, this interaction as the primary mmoa is supported in the published literature [7,9].

Bioactivity Comments

We have been unable to find a publicly available binding affinity for interaction between epratuzumab and CD22. However, this interaction as the primary mmoa is supported in the published literature [7,9].