Ligand id: 8400

Name: anacetrapib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 9
Topological polar surface area 38.77
Molecular weight 637.17
XLogP 11.08
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
Anacetrapib inhibits the cholesteryl ester transfer activity of human recombinant CETP with an IC50 value of 17.2nM [4].