Synonyms: GS-6615 | GS6615
Compound class:
Synthetic organic
Comment: Eleclazine is a sodium channel inhibitor, modulating cardiac late Na+ currents via the Nav1.5 (gene symbol SCN5A) channel. The compound is a dihydrobenzodiazepine type structure. Dihydrobenzodiazepine scaffolds are being developed as α-helix mimetics, with the potential to inhibit protein-protein interactions [1,3-5]. This chemical structure and its use is covered by patent US20150038489 [2].
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Bioactivity Comments |
To date no data for this compound has been published in a peer reviewed article. We have tagged the primary target based on the patent description [2]. |
Selectivity at ion channels | ||||||||||||||||||||||||||||||||||
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