compound A [PMID 24997608]

Ligand id: 8418

Name: compound A [PMID 24997608]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 49.77
Molecular weight 405.13
XLogP 5.85
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
CpdA acts as a potent anti-inflammatory agent in vitro and in vivo, and improves glucose tolerance (and other diabetes related parameters) in a mouse model of type 2 diabetes [1].
Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
FFA4 receptor Agonist Agonist 7.6 pEC50 - 1
pEC50 7.6 [1]
Description: Fluorometric calcium assay using FLIPR methodology.