compound A [PMID 24997608]

Ligand id: 8418

Name: compound A [PMID 24997608]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 49.77
Molecular weight 405.13
XLogP 5.85
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Oh da Y, Walenta E, Akiyama TE, Lagakos WS, Lackey D, Pessentheiner AR, Sasik R, Hah N, Chi TJ, Cox JM et al.. (2014)
A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice.
Nat. Med., 20 (8): 942-7. [PMID:24997608]
2. Oh DY, Talukdar S, Bae EJ, Imamura T, Morinaga H, Fan W, Li P, Lu WJ, Watkins SM, Olefsky JM. (2010)
GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects.
Cell, 142 (5): 687-98. [PMID:20813258]