beloranib

Ligand id: 8445

Name: beloranib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 12
Topological polar surface area 73.06
Molecular weight 499.29
XLogP 4.49
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Bioactivity Comments
An inhihitory constant for beloranib inhibition of MetAP2 enzymatic activity has not been published. We tag the enzyme as the compound's primary molecular target based on preclinical results [1,3].
Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
Methionyl aminopeptidase 2 Inhibitor Inhibition - - - 3
[3]