Synonyms: CKD-732 [2] | O-(4-(2-Dimethylaminoethoxy)-trans-cinnamoyl)fumagillol | ZGN 440 | ZGN-440
Compound class:
Synthetic organic
Comment: Beloranib is an investigational drug candidate for the treatment of obesity. The compound is a synthetic derivative of the antimicrobial agent fumagillin, from Aspergillus fumigatus. Beloranib is administered by subcutaneous injection.
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Bioactivity Comments |
An inhihitory constant for beloranib inhibition of MetAP2 enzymatic activity has not been published. We tag the enzyme as the compound's primary molecular target based on preclinical results [1,3]. |
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