ARI-3099

Ligand id: 8563

Name: ARI-3099

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 102.76
Molecular weight 291.14
XLogP -0.23
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
fibroblast activation protein alpha Inhibitor Inhibition 7.4 pIC50 - 2
pIC50 7.4 (IC50 3.6x10-8 M) [2]
acylaminoacyl-peptide hydrolase Inhibitor Inhibition 7.0 pIC50 - 1
pIC50 7.0 (IC50 1.04x10-7 M) [1]
Description: Substrate (Ac-Ala-AMC) assay.