compound 37 [PMID: 24418773]

Ligand id: 8612

Name: compound 37 [PMID: 24418773]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 7
Rotatable bonds 15
Topological polar surface area 183.42
Molecular weight 522.3
XLogP 1.93
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
protein C, inactivator of coagulation factors Va and VIIIa Inhibitor Inhibition 7.4 pKi - 1
pKi 7.4 (Ki 4x10-8 M) [1]