compound 40 [PMID: 10602705]

Ligand id: 8630

Name: compound 40 [PMID: 10602705]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 12
Hydrogen bond donors 5
Rotatable bonds 13
Topological polar surface area 251.58
Molecular weight 483.13
XLogP -3.83
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at Mouse enzymes
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Target Type Action Affinity Units Concentration range (M) Reference
Glutamyl aminopeptidase Inhibitor Inhibition 9.1 pKi - 1
pKi 9.1 (Ki 8.73x10-10 M) [1]