Ligand id: 9004

Name: ADL5859

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 61.8
Molecular weight 392.21
XLogP 4.16
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
Note that the hydrochloride salt (PubChem CID 46931003) may have been used to generate some bioactivity data.
Selectivity at Human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
δ receptor Agonist Agonist 9.1 pKi - 1
pKi 9.1 (Ki 8.4x10-10 M) [1]
μ receptor Agonist Agonist 7.5 pKi - 1
pKi 7.5 (Ki 3.2x10-8 M) [1]
κ receptor Agonist Agonist 7.4 pKi - 1
pKi 7.4 (Ki 3.7x10-8 M) [1]