ARL 67156

Ligand id: 9030

Name: ARL 67156

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 17
Hydrogen bond donors 6
Rotatable bonds 11
Topological polar surface area 276.55
Molecular weight 716.9
XLogP -2.7
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
Has weak antagonist activity at purinoceptors [2].
Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
ectonucleoside triphosphate diphosphohydrolase 1 Rn Inhibitor Inhibition 4.6 pKi - 1
pKi 4.6 (Ki 2.7x10-5 M) [1]