ARL 67156

Ligand id: 9030

Name: ARL 67156

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 17
Hydrogen bond donors 6
Rotatable bonds 11
Topological polar surface area 276.55
Molecular weight 716.9
XLogP -2.7
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

1. Brunschweiger A, Iqbal J, Umbach F, Scheiff AB, Munkonda MN, Sévigny J, Knowles AF, Müller CE. (2008)
Selective nucleoside triphosphate diphosphohydrolase-2 (NTPDase2) inhibitors: nucleotide mimetics derived from uridine-5'-carboxamide.
J. Med. Chem., 51 (15): 4518-28. [PMID:18630897]
2. Crack BE, Pollard CE, Beukers MW, Roberts SM, Hunt SF, Ingall AH, McKechnie KC, IJzerman AP, Leff P. (1995)
Pharmacological and biochemical analysis of FPL 67156, a novel, selective inhibitor of ecto-ATPase.
Br. J. Pharmacol., 114 (2): 475-81. [PMID:7533620]