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Synonyms: OPN 7486 | OPN-7486 | PLX-7486
Compound class:
Synthetic organic
Comment: PLX7486 is a small molecule CSF1R/TRK/Fms kinases inhibitor. It is orally available, potent and selective, with attractive pharmaceutical properties and is being investiagted for its anti-neoplastic action [1].
The chemical structure of PLX7486 has not yet been disclosed. We will show this as soon as it is openly available. |
| Bioactivity Comments |
| PLX7486 also inhibits the neurotrophic tyrosine kinases (Trks, or NTRKs). |
