Ligand id: 9128

Name: megestrol

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 54.37
Molecular weight 342.22
XLogP 3.31
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Bioactivity Comments
The only bioactivity data available appears to be DRUGMATRIX radioligand binding (on ChEMBL) for megestrol acetate vs. the bovine progesterone receptor, which gives an IC50 of 11nM.