2'3'-cGAMP

Ligand id: 9207

Name: 2'3'-cGAMP

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 23
Hydrogen bond donors 8
Rotatable bonds 2
Topological polar surface area 344.65
Molecular weight 675.11
XLogP -6.4
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human other protein targets
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
transmembrane protein 173 Agonist Agonist 8.3 – 8.4 pKd - 2
pKd 8.3 – 8.4 (Kd 4.59x10-9 – 3.79x10-9 M) [2]