Ligand id: 9374

Name: CX-5279

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 102.86
Molecular weight 438.12
XLogP 4.37
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
Casein kinase 2 Hs Inhibitor Inhibition 9.0 pIC50 - 1
pIC50 9.0 (IC50 9.1x10-10 M) [1]
Description: Recombinant human CK2 holoenzyme containiny wild-type alpha subunits.
Casein kinase 2 Rn Inhibitor Inhibition 8.6 pIC50 - 1
pIC50 8.6 (IC50 2.73x10-9 M) [1]
Description: Native CK2 isolated from rat liver
Pim-1 proto-oncogene, serine/threonine kinase Hs Inhibitor Inhibition 5.1 pIC50 - 1
pIC50 5.1 (IC50 8.52x10-6 M) [1]