CX-5279

Ligand id: 9374

Name: CX-5279

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 102.86
Molecular weight 438.12
XLogP 4.37
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Battistutta R, Cozza G, Pierre F, Papinutto E, Lolli G, Sarno S, O'Brien SE, Siddiqui-Jain A, Haddach M, Anderes K et al.. (2011)
Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer.
Biochemistry50 (39): 8478-88. [PMID:21870818]