3 alpha-aminocholestane

Ligand id: 9564

Name: 3 alpha-aminocholestane

Abbreviated name: 3AC

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 26.02
Molecular weight 387.39
XLogP 11.72
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Bioactivity Comments
3AC is selective for SHIP1 over the related inositol phosphatases SHIP2 and PTEN.
Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
INPP5D Hs Inhibitor Inhibition - - - 1