BIA 10-2639

Ligand id: 9603

Name: BIA 10-2639

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 51.02
Molecular weight 284.16
XLogP 2.48
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
BIA 10-2639 exhibits equivalent activities to BIA 10-2474 in the assays reported in [1].
Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
Fatty acid amide hydrolase Inhibitor Inhibition 7.2 – 7.3 pIC50 - 1
pIC50 7.2 – 7.3 (IC50 7x10-8 – 5x10-8 M) [1]
Description: In situ inhibition in HEK3293T cells expressing human FAAH.