BIA 10-2639

Ligand id: 9603

Name: BIA 10-2639

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 51.02
Molecular weight 284.16
XLogP 2.48
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
BIA 10-2639 exhibits equivalent activities to BIA 10-2474 in the assays reported in [1].
Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
Fatty acid amide hydrolase Hs Inhibitor Inhibition 7.2 – 7.3 pIC50 - 1
pIC50 7.2 – 7.3 (IC50 7x10-8 – 5x10-8 M) [1]
Description: In situ inhibition in HEK3293T cells expressing human FAAH.