Synonyms: BRL-42810 | BRL42810 | Famvir® | FCV
famciclovir is an approved drug (FDA (1994), UK (1995))
Compound class:
Synthetic organic
Comment: Famciclovir is an orally-delivered, prodrug of the antiviral agent penciclovir [1]. The active metabolite, penciclovir triphosphate, has activity against Herpes viruses and varicella-zoster. Penciclovir triphosphate is a nucleoside analogue that inhibits viral DNA replication by interfering competitively with DNA polymerase.
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No information available. |
Summary of Clinical Use |
Famciclovir is used to treat herpes zoster and simplex virus infections. |
Pharmacokinetics |
Biotransformation/Metabolism |
After oral dosing more than half the dose of famciclovir is absorbed and rapidly converted to penciclovir [1]. |
External links |
For extended ADME data see the following: Drugs.com |