bimatoprost (free acid form)

Ligand id: 1959

Name: bimatoprost (free acid form)

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 11
Topological polar surface area 97.99
Molecular weight 388.22
XLogP 4.97
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Administered as the prodrug bimatoprost which is used in the management of open angle glaucoma or ocular hypertension.
Mechanism Of Action and Pharmacodynamic Effects
Prodrug bimatoprost and the free acid from resulting from the drug's in vivo metabolism decrease the pressure within the eye by mimicking the action of prostaglandin PGF in increasing the outflow of aqueous humor from the eyeball.