Ligand id: 204

Name: fluphenazine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 55.25
Molecular weight 437.17
XLogP 4.41
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Fluphenazineis used to treat psychotic disorders such as schizophrenia.
Mechanism Of Action and Pharmacodynamic Effects
Fluphenazine is a dopamine D2 receptor antagonist. This drug's antipsychotic action arises from increased levels of the centrally acting monoamines serotonin and noradrenaline caused by D2 receptor antagonism.