Ligand id: 2139

Name: TRH

Species: Human, Mouse, Rat

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Structure and Physico-chemical Properties

2D Structure
No information available.
Summary of Clinical Use
Protirelin is mainly used as a diagnostic tool to test pituitary function in patients with thyroid hormone disorders, in order to rule out pituitary gland problems. Protirelin has been used to treat spinocerebellar degeneration and disturbance of consciousness [2].
Mechanism Of Action and Pharmacodynamic Effects
Protirelin stimulates the release of thyroid-stimulating hormone and prolactin from anterior pituitary cells which express the TRHR.