mosapride

Ligand id: 242

Name: mosapride

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 76.82
Molecular weight 421.16
XLogP 2.59
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Mosapride is not approved by the US FDA or EMA. Other national approval agencies (mainly in South America and East Asia) have authorised its clinical use. Where approved, mosapride is used to treat gastrointestinal disorders [2], as it acts to accelerate gastric emptying.
Mechanism Of Action and Pharmacodynamic Effects
Mosapride a selective agonist of the serotonin 5-HT4 receptor [3].