Ligand id: 2510

Name: quinine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 45.59
Molecular weight 324.18
XLogP 2.66
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of malaria and leg cramps, although the latter use is no longer recommended due to the risk of thrombocytopenia.
Mechanism Of Action and Pharmacodynamic Effects
Believed to be toxic to the malarial parasite. Mechanism for easing leg cramps is undetermined.
External links