Ligand id: 2523

Name: nimodipine

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: nimodipine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 117
Molecular weight 418.17
XLogP 4.6
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used as an adjunct to improve neurologic outcome following subarachnoid hemorrhage from ruptured intracranial berry aneurysms.
Mechanism Of Action and Pharmacodynamic Effects
The exact mechanism of action of nimodipine is unknown; however, for an overview of its actions please see the DrugBank entry linked to from this ligand page.
External links