Ligand id: 2566

Name: amiodarone

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 11
Topological polar surface area 42.68
Molecular weight 645.02
XLogP 7.78
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat angina and arrhythmias.
Mechanism Of Action and Pharmacodynamic Effects
Principally an ion channel blocker acting on sodium and potasium channels. It also appears to have β-blocker-like action (via β-adrenoceptors).
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