Ligand id: 2941

Name: lorcaserin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 12.03
Molecular weight 195.08
XLogP 2.69
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Approved as a weight-loss drug to be used along side caloric restriction and increased physical activity in the chronic management of obesity, in patients with BMI≥27kg/m2. Clinical formulations contain lorcaserin hydrochloride (PubChem CID 11673085).
Mechanism Of Action and Pharmacodynamic Effects
Lorcaserin is a selective 5-HT2C receptor agonist and acts as an anorectic, achieving weight-loss.
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