Ligand id: 305

Name: pilocarpine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 44.12
Molecular weight 208.12
XLogP 1.31
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of glaucoma and xerostomia.
Mechanism Of Action and Pharmacodynamic Effects
Parasympathomimetic cholinergic agent, which increases secretion in by the exocrine glands, and when given topically to the eyes produces contraction of the iris sphincter muscle and ciliary muscle by stimulating muscarinic receptors.
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