pilocarpine

Ligand id: 305

Name: pilocarpine

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: pilocarpine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 44.12
Molecular weight 208.12
XLogP 1.31
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1974))
IUPAC Name
(3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]oxolan-2-one
Synonyms
pilocarpine hydrochloride | pilocarpine nitrate | pilokarpin | Salagen®
Database Links
BindingDB Ligand 50008072
CAS Registry No. 92-13-7
ChEBI CHEBI:8207
ChEMBL Ligand CHEMBL550
DrugBank Ligand DB01085
PubChem CID 5910
RCSB PDB Ligand 9PL
Search Google for chemical match using the InChIKey QCHFTSOMWOSFHM-WPRPVWTQSA-N
Search Google for chemicals with the same backbone QCHFTSOMWOSFHM
Search UniChem for chemical match using the InChIKey QCHFTSOMWOSFHM-WPRPVWTQSA-N
Search UniChem for chemicals with the same backbone QCHFTSOMWOSFHM
Wikipedia Pilocarpine
Comments
Pilocarpine is a parasympathomimetic alkaloid type cholinergic drug, exerting its clinical effects via activation of muscarinic acetylcholine M3 receptors.