Ligand id: 325

Name: ipratropium

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 46.53
Molecular weight 332.22
XLogP 4.23
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat bronchospasm associated with chronic obstructive pulmonary disease (COPD).
Mechanism Of Action and Pharmacodynamic Effects
Ipratropium is a muscarinic cholinergic receptor blocker, the actions of which lead to a decrease in the formation of cGMP, which in turn leads to decreased contractility of smooth muscle.