Ligand id: 354

Name: dexetimide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 49.41
Molecular weight 362.2
XLogP 5.87
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Dexetimide is approved in Luxembourg and Netherlands (as Tremblex®) to treat neuroleptic-induced Parkinsonian extrapyramidal side-effects [1-2].
Mechanism Of Action and Pharmacodynamic Effects
Dexetimide is a muscarinic antagonist.