salicylic acid

Ligand id: 4306

Name: salicylic acid

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 1
Topological polar surface area 57.53
Molecular weight 138.03
XLogP 1.71
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
An additive in many skin care products used in the treatment of acne, psoriasis, callouses, corns, kertosis pilaris and warts.
Mechanism Of Action and Pharmacodynamic Effects
It has been proposed that the inhibition of prostaglandin biosynthesis by salicylic acid (and aspirin) results from inhibitiion of upstream expression of cyclooxygenase genes, rather than direct inhibition of enzyme activity [1].
External links