triflupromazine

Ligand id: 4330

Name: triflupromazine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Topological polar surface area 31.78
Molecular weight 352.12
XLogP 5.48
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used for the management of psychoses, and the control of nausea and vomiting.
Mechanism Of Action and Pharmacodynamic Effects
Triflupromazine is an antagonist of the dopamine D2 receptor. For an overview of the mechanism of action of triflupromazine, please see the DrugBank link on the Summary tab of this ligand page.