zolpidem

Ligand id: 4348

Name: zolpidem

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 37.61
Molecular weight 307.17
XLogP 4.53
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
A sedative or hypnotic agent used in the treatment of insomnia.
Mechanism Of Action and Pharmacodynamic Effects
Zolpidem is an agonist of the GABAA receptor with highest affinity at the α1 subunit. The positive modulation of the GABAA receptor complex by zolpidem increases its affinity for GABA.
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