Ligand id: 4348

Name: zolpidem

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 37.61
Molecular weight 307.17
XLogP 4.53
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Hadingham KL, Wafford KA, Thompson SA, Palmer KJ, Whiting PJ. (1995)
Expression and pharmacology of human GABAA receptors containing gamma 3 subunits.
Eur. J. Pharmacol., 291 (3): 301-9. [PMID:8719414]
2. Hadingham KL, Wingrove P, Le Bourdelles B, Palmer KJ, Ragan CI, Whiting PJ. (1993)
Cloning of cDNA sequences encoding human alpha 2 and alpha 3 gamma-aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant alpha 1-, alpha 2-, alpha 3-, and alpha 5-containing human gamma-aminobutyric acidA receptors.
Mol. Pharmacol., 43 (6): 970-5. [PMID:8391122]
3. Scholze P, Ebert V, Sieghart W. (1996)
Affinity of various ligands for GABAA receptors containing alpha 4 beta 3 gamma 2, alpha 4 gamma 2, or alpha 1 beta 3 gamma 2 subunits.
Eur. J. Pharmacol., 304 (1-3): 155-62. [PMID:8813598]