valacyclovir

Ligand id: 4824

Name: valacyclovir

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 4
Rotatable bonds 8
Topological polar surface area 146.52
Molecular weight 325.16
XLogP -1.01
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment and suppression of cold sores, herpes zoster (shingles), and genital herpes.
Mechanism Of Action and Pharmacodynamic Effects
The phosphorylation products of valacyclovir inhibit herpes viral DNA replication by competitive inhibition of viral DNA polymerase.
External links