zalcitabine

Ligand id: 4828

Name: zalcitabine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 87.82
Molecular weight 212.1
XLogP -0.69
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of HIV/AIDs in conjunction with other antiretrovirals.
Mechanism Of Action and Pharmacodynamic Effects
Inhibits nucleoside reverse transcriptase in HIV-1 leading to the termination of DNA growth.