Ligand id: 483

Name: methoxamine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 64.71
Molecular weight 211.12
XLogP 0.61
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment and management of hypotension. There is no information regarding approval for medical use of methoxamine on the US FDA website. According to the FDA's International Drug Names list this drug is only used in Japan.
Mechanism Of Action and Pharmacodynamic Effects
Selective agonist of alpha-1 adrenergic receptors, which leads to an increase in systemic blood pressure.