methoxamine

Ligand id: 483

Name: methoxamine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 64.71
Molecular weight 211.12
XLogP 0.61
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Minneman KP, Theroux TL, Hollinger S, Han C, Esbenshade TA. (1994)
Selectivity of agonists for cloned α1-adrenergic receptor subtypes.
Mol. Pharmacol.46: 929-936. [PMID:7969082]
2. Shibata K, Foglar R, Horie K, Obika K, Sakamoto A, Ogawa S, Tsujimoto G. (1995)
KMD-3213, a novel, potent, alpha 1a-adrenoceptor-selective antagonist: characterization using recombinant human alpha 1-adrenoceptors and native tissues.
Mol. Pharmacol.48: 250-258. [PMID:7651358]
3. Taniguchi T, Inagaki R, Murata S, Akiba I, Muramatsu I. (1999)
Microphysiometric analysis of human alpha1a-adrenoceptor expressed in Chinese hamster ovary cells.
Br J Pharmacol127: 962-968. [PMID:10433504]