insulin-like growth factor 1

Ligand id: 4971

Name: insulin-like growth factor 1

Abbreviated name: IGF-1

Species: Human

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Summary of Clinical Use
In its recombinant form as the approved drug mecasermin, IGF1 is used to improve growth in pediatric patients with primary insulin-like growth factor 1 deficiency.
Mechanism Of Action and Pharmacodynamic Effects
Mecasermin acts through the type 1 IGF-1 receptor and mimics the effects of endogenous IGF-1 on the growth of bones and muscles.