Ligand id: 517

Name: xylometazoline

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 24.39
Molecular weight 244.19
XLogP 5.78
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Xylometazoline is a component of many nasal decongestants which are used to relieve nasal congestion and minor inflammation associated with allergies and colds. Xylometazoline is available as an over-the-counter (OTC) medication in many countries.
Mechanism Of Action and Pharmacodynamic Effects
Induces vasoconstriction in the nasal muscosa via agonism of α-adrenoceptors.
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