Ligand id: 517

Name: xylometazoline

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 24.39
Molecular weight 244.19
XLogP 5.78
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
As we have been unable to find publicly available affinity data for this drug (at the human target) to substantiate its MMOA, we have not mapped a primary drug target.
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
α1D-adrenoceptor Rn Agonist Full agonist 6.0 pKi - 1
pKi 6.0 [1]
TAAR4P Mm Agonist Full agonist - - - 2