Ligand id: 520

Name: brimonidine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 62.2
Molecular weight 291.01
XLogP 1.65
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of glaucoma. Low dose brimonidine tartrate (0.025%) ophthalmic solution is effective against ocular redness.
Mechanism Of Action and Pharmacodynamic Effects
Brimonidine appears to reduce intraocular pressure by reducing both aqueous humor production and outflow from the eyeball.