BI-2536

Ligand id: 5666

Name: BI-2536

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 102.93
Molecular weight 521.31
XLogP 2.73
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Several Phase II clinical trials assessing BI-2536 have been completed. Indications included non-small-cell lung cancer (NSCLC), relapsed/refactory acute myeloid leukemia (AML) and prostate, breast, endometrial and head and neck cancers. Click here to view a complete listing of Phase II BI-2536 trials registered with ClinicalTrials.gov.