Ligand id: 5676

Name: CI-1040

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 50.36
Molecular weight 477.98
XLogP 5.49
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
CI-1040 was assessed in two completed Phase II clinical trials. Indications investigated included advanced breast cancer, colorectal cancer, non-small cell lung cancer and pancreatic cancer. Development of this compound was then terminated.