BAY 11-7082

Ligand id: 5934

Name: BAY 11-7082

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 66.31
Molecular weight 207.04
XLogP 2.31
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Mechanism Of Action and Pharmacodynamic Effects
BAY 11-7082 is reported to bond covalently with cysteine residues in Ubc13 and UbcH& and that this blocks their ability to form poly-ubiquitin chains [4].