dovitinib

Ligand id: 5962

Name: dovitinib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 1
Topological polar surface area 85.99
Molecular weight 392.18
XLogP 2.29
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Visit ClinicalTrials.gov to view currently registered drug trials involving this compound.
Mechanism Of Action and Pharmacodynamic Effects
This compound inhibits key receptor tyrosine kinases that are implicated in tumor vasculature formation and maintenance, and which underlie tumor progression and metastasis.