Ligand id: 6310

Name: vildagliptin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 76.36
Molecular weight 303.19
XLogP 0.79
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the management of type 2 diabetes. This drug is not approved by the US FDA.
Mechanism Of Action and Pharmacodynamic Effects
Inhibition of dipeptidyl peptidase-4 (DPP-4) prevents the inactivation of GLP-1 by DPP-4, enabling GLP-1 to potentiate insulin secretion in beta cells.
External links