vildagliptin

Ligand id: 6310

Name: vildagliptin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 76.36
Molecular weight 303.19
XLogP 0.79
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (EMA (2007))
IUPAC Name
(2S)-1-[2-[(3-hydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carbonitrile
International Nonproprietary Names
INN number INN
8399 vildagliptin
Synonyms
Galvus® | LAF-237 | NVP-LAF237
Database Links
CAS Registry No. 274901-16-5
ChEMBL Ligand CHEMBL142703
DrugBank Ligand DB04876
PubChem CID 6918537
Search Google for chemical match using the InChIKey SYOKIDBDQMKNDQ-XWTIBIIYSA-N
Search Google for chemicals with the same backbone SYOKIDBDQMKNDQ
Search PubMed clinical trials vildagliptin
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Search UniChem for chemical match using the InChIKey SYOKIDBDQMKNDQ-XWTIBIIYSA-N
Search UniChem for chemicals with the same backbone SYOKIDBDQMKNDQ
SynPHARM 78481 (in complex with dipeptidyl peptidase 4)
Wikipedia Vildagliptin
Comments
Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor class anti-diabetic drug.